FACTS
#1 cause of hydrocephalus in preterm infants
Pathophysiology: alterations of cerebral blood flow through germinal matrix can lead to hemorrhage, as these vessels to not have typical components of the BBB. The matrix is a well-vascularized periventricular sub-ependymal area of the brain.
Origin of bleeds
- PREMATURE babies IVH --> germinal matrix
- TERM babies IVH --> choroid plexus
A/P
daily OFCs
serial lumbar taps (pediatricians/neonatologists)
serial US
serial OFCs (use corrected age!)
CSF diversion:
- Ventriculoperitoneal Shunts
- Ventriculo-subgalael shunts
- Ommaya
- ETV (low success score)
NICU protocol
- (pre Omaya): LP taps per NICU protocol
- (post Omaya): Omaya taps per NICU protocol
Grades of IVH
Grade | Blood burden | Ventriculomegaly / Hydro |
1 | confined to germinal matrix | none |
2 | blood in ventricles | none, although may go on to develop hydro |
3 | blood in ventricles | yes |
4 | blood in ventricles + ruptures/dissection of clot into surrounding white matter | yes |