IVH of Prematurity

FACTS

#1 cause of hydrocephalus in preterm infants
Pathophysiology: alterations of cerebral blood flow through germinal matrix can lead to hemorrhage, as these vessels to not have typical components of the BBB. The matrix is a well-vascularized periventricular sub-ependymal area of the brain.
Origin of bleeds
  • PREMATURE babies IVH --> germinal matrix
  • TERM babies IVH --> choroid plexus

HPI

  • Common co-morbidities: apnea of prematurity, respiratory distress w/ ventilator dependence, anemia, E faecalis sepsis, PDA
  • Check for bradycardia / desaturations and ask NICU nurses
  • check weight (cannot operate on a human being < 2kg)

PHYSICAL EXAM

check fontanelles
evaluate for dilated scalp veins
evaluate for sun-setting of pupils (forced downgaze)
if severe: transillumination of cranium
evaluate symmetry of spontaneous movements (hemorrhage may cause contralateral hemiparesis)

IMAGING

US is best modality, no transport, no radition
MRI is okay modality of child is safe to transport
CT least desirable, involves transport and radiation
evalute for periventricular leukomalacia

A/P
daily OFCs
serial lumbar taps (pediatricians/neonatologists)
serial US
serial OFCs (use corrected age!)
CSF diversion:
  • Ventriculoperitoneal Shunts
  • Ventriculo-subgalael shunts
  • Ommaya
  • ETV (low success score)
NICU protocol
  • (pre Omaya): LP taps per NICU protocol
  • (post Omaya): Omaya taps per NICU protocol

Grades of IVH

Grade
Blood burden
Ventriculomegaly / Hydro
1
confined to germinal matrix
none
2
blood in ventricles
none, although may go on to develop hydro
3
blood in ventricles
yes
4
blood in ventricles + ruptures/dissection of clot into surrounding white matter
yes

Pre-Omaya Protocol

1704733485747-725.png

Post-Omaya

1704733602963-888.png